SPKSB.ORG / SPECIAL PROVISION FOR KINETIC SYSTEMS BIOLOGY
Mission / Projects / Personnel
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SPKSB

Special Provision for Kinetic Systems Biology

Projects

Current research unit and technical focus

Projects

Internal projects are classified as "Units."

Unit-00 is the sole active project.

Unit-00

Protein Evolutionary Rates.

Unit-00 is focused on predicting a key evolutionary biology ratio known as dN/dS using Amino Acid (AA) sequences and tertiary protein structures.

Predictive Target

dN/dS determines how a protein changes over time based on changes to the gene expressing it.

The unit therefore treats sequence and structure as linked evidence for evolutionary rate behavior.

Input Modalities

  • Amino Acid (AA) sequences
  • Tertiary protein structures
  • Kinetic and mechanistic interpretation where appropriate

Operational Status

Unit-00 is currently the only active unit in the SPKSB registry.

The working expectation is that unit progress contributes directly to the organization-wide paper or preprint cadence.